In a podium presentation, each student presents their research story in a live lecture format lasting no more than eight minutes. All are welcome to attend!
Morning Session (9-10 a.m.)
Room 417: Who We Are, What We Create, What We Leave Behind
Andrew Rivadeneira, Classical Civilization
Project Advisor: Dr. Jeffrey Kramer
Abstract: Troy was once thought to have been just a myth, instead it was a very real city. Carl W. Blegen and Marion Rawson led the University of Cincinnati excavation at the site from 1932-1938, following in the footsteps of Heinrich Schliemann and William Dörpfeld. These excavations were made possible due to the support and participation of William T. Semple, the chair of the Department of Classics, and Louise Taft Semple. This is a virtual exhibition on the Archaeology of Troy. It focuses on these excavations and their finds. The exhibition highlights unique features of the nine phases of Troy. Images are used from the excavation to visually represent some of these features. I also discuss the pottery of each phase in more detail with examples and pottery charts. This project was done in conjunction with the University of Cincinnati's Classics Archives and Collections. The goal is to bring to life such an important archaeological site and the University's role.
Noah Csendes, Information Systems
Project Advisor: Dr. Michael Jones
Abstract: An independent study in the field of cryptoeconomics to develop and execute a formal program by which donors can invest in student groups to source, build, customize, and manage cryptocurrency mining systems in the Digital Futures Cryptoeconomics lab space. The program will serve to extend learning opportunities to interested students as well as provide greater visibility and presence in the cryptoeconomics industry at the University of Cincinnati.
Quinn Davidson, Business Analytics
Project Advisor: Dr. Daniel Peat
Abstract: According to social identity theory, individuals have many competing identities that explain intergroup behavior. Organizations often develop diversity and inclusion programs based on these social identities to build trust and increase commitment among employees. However, organizations often overlook military veteran identity when developing these programs. In this study of 139 veterans, across a wide spectrum of demographics characteristics, we use cluster analysis and find that many aspects of veterans' lives are important to them; including, but not limited to, military, social, and personal identities. However, their veteran identity is the strongest and most influential identity. These results are especially prevalent in certain backgrounds, such as the Air Force and those who have been in the military for 13-19 years. Those who have been in the military have a strong, long lasting military identity that organizations should consider when implementing diversity and inclusion programs since it brings a different viewpoint on topics that an organization would not be able to get otherwise. Additionally, this identity transcends others that organizations tend to focus on more often.
Room 419: Culture and Technology
Elizabeth Love, Classical Languages
Project Advisor: Dr. Amy Lind
Abstract: The American Evangelical Movement holds a large number of adherents, and as such, has diverged into a innumerable variety of beliefs and practices. Central to all of these beliefs, however, is what is called "purity culture" - an evangelical dogma that emphasizes chastity among unmarried people, rejection of "fornication," and the devotion of a woman to her husband. This burden has real-world implications for women bearing it; according to Uecker, Mormons and conservative protestants are much more likely to marry early than the general population. Cassidy and Turner, writing for UNICEF, report that 86% of children married in the United States between 2000 and 2018 were girls. When one looks at the tenants of purity culture, however, and then compares it to the reproductive platforms of white nationalist groups, one can find a lot of overlap. This is not an accident. Many elements of purity culture support proposed strategies adopted by white nationalists, particularly the "Quiverfull" Movement, so white nationalists have an incentive to promote the moralization platform. Evangelicals often promote the white nationalist platform on immigration for its resistance to the immigration of Muslims to the United States, though they can often go farther. This paper intends to explore the ties between these supposedly separate movements and show that they are not as different as they would like the outside viewer to believe.
Rebecca Gilligan, Mechanical Engineering
Project Advisor: Dr. Kelly Cohen
The objective of the All-Terrain Aerial Robotic Interface (ATARI) project is to develop and test a collaborative unmanned aerial vehicle (UAV) and unmanned ground vehicle (UGV) pair to allow takeoff and landing on uneven terrain and increase useful flight time. The UGV serves as a dynamic takeoff and landing platform for the UAV. In addition, it features a levelling platform, and is capable of handling various testing terrain. The UAV will test sensor options for autonomous takeoff and landing on the levelling platform. Phase 1 designed a 690mm hexacopter that features an IR-Lock sensor as the first autonomous landing option to be tested. The UGV is 600 x 600 x 300 mm with a 4-wheel skid-steer configuration. The UGV features a self-levelling, landing platform for the UAV. Both vehicles use a Pixhawk Cube Orange autopilot with Ardupilot firmware and a Raspberry Pi as the on-board computer, running the UAV MASTER Lab's custom software suite. Phase 2 involves the construction of the prototype vehicles, software development, and basic testing (in progress). The vehicles are nearly ready to begin flight testing once requirements are verified and a Test Readiness Review is completed. Phase 3 involves dynamic collaborative testing. Vehicle testing will follow a crawl-walk-run approach, beginning with subsystems and independent flight/drive before moving on to collaborative testing, and finishing with a demonstration mission. Phase 4 will involve implementing additional features and capabilities such as recharging, adding manipulators, testing additional payloads, and scaling up the project to support larger vehicles and swarming.
Maya Gulani, Political Science and International Affairs and German Studies
Project Advisor: Dr. Rina Williams
Abstract: Following its introduction to India in the late 19th century, the harmonium has simultaneously been integrated into many Indian musical traditions while also facing intense skepticism and backlash. Most explanations for this backlash have centered on technical music aspects, and I agree that there is validity to these musical arguments. However, I posit that the full extent of the pushback against the harmonium in India can only be fully explained when the nationalist ideologies prevalent in Indian society leading up to, during, and following the independence era are taken into account. While the harmonium's role in Indian music has been discussed by musicologists, this paper approaches the subject from a political perspective in order to study Indian nationalism through its influence on art. Thus, while I address the musical reasonings behind the criticisms of the harmonium, I focus my discussion on broader nationalist ideologies in India, demonstrated and contextualized by the negative reception of the harmonium. I examine three factors together to highlight this relationship: (a) the failure of musical arguments to explain the full extent of its negative reception; (b) the independence-era desire to create a defined Indian culture; and (c) the politicization of the harmonium, capitulated by All India Radio's ban on the instrument.
Room 425: Innovation and Access
Helena Li, Medical Sciences
Project Advisor: Dr. Xueheng Zhao
Abstract: Quantitative determination of nucleosides and nucleotides in cells is fundamental to understanding nucleotide biosynthesis, energy metabolism, and signaling pathways in diseases. Current mass spectrometry-based methods give limited coverage and high rates of false identifications. Ultrahigh-performance liquid chromatography coupled with high-resolution mass spectrometry (UHPLC-HRMS) can provide confident qualification of nucleotides. The objective of this study was to develop a robust method to quantify metabolites from de novo and salvage pathways in Mll-Af9 knock-in acute myeloid leukemia (AML) mouse models with increased coverage and high sensitivity for analysis. By a two-step protein precipitation method, intracellular nucleotides/nucleosides and quality controls were prepared and extracted from known analyte concentrations in water. Parallel reaction monitoring (PRM) MS on two different columns was used to measure 28 nucleotide metabolites against internal standards. Unlike traditional methods, PRM with HRMS gives confident identifications while eliminating intermolecular interferences. Resulting spectra give abundant fragmentation derived from three main structural subunits. With two columns and a 30-minute run time, a larger coverage and separation of historically challenging analytes was achieved. This method was illustrated in AML mouse model cell lines containing a gene mutation with adverse outcomes in leukemia patients and validated by linearity, sensitivity, accuracy, and reproducibility. Preliminary data revealed the mutation leads to unrestrained leukemia cell proliferation, likely due to upregulated purine and pyrimidine synthesis for increased dNTPs for cell growth. A comprehensive and validated MS-based method targeting biosynthesis pathways was developed to profile 28 nucleotides and nucleosides, applicable to leukemia mouse models and other nucleotide derivatives and matrices.
Nicholas Shaw, Medical Sciences
Project Advisor: Dr. Tom Seegar
Abstract: Proteins are the essential machines that perform the major functions of cells. The protein that I study is called a disintegrin and metalloprotease 10 (ADAM10) which processes and releases different molecules from a cell through an essential process called ectodomain shedding. When ADAM10's function is dysregulated, Alzheimer's disease and cancer can occur. Because the serious diseases linked with ADAM10, efforts have been made to produce pharmaceutical compounds targeting ADAM10. Unfortunately, these compounds have had many adverse side effects, making them not clinically useful. However, ADAM10 is inhibited naturally through one of its own domains, a functional subunit of the protein. This inhibitory domain of ADAM10, called it's prodomain, has a molecular composition unique to ADAM10, so understanding what the prodomain's structure would allow for completely novel drugs to be made that avoid harmful side effects by specifically targeting ADAM10. To gain the structural information about the prodomain of ADAM10, I produced and purified millions of copies of the prodomain, and then screened them for a condition that would allow them to form into a crystal. After identification of a suitable crystallization condition, other similar conditions were screened to optimize crystal growth which would allow me to determine the structure with greater precision. In the future, data will be collected from the crystals to reveal the three-dimensional structure of the ADAM10 prodomain. This three-dimensional structure will provide essential information for developing therapies for diseases in which ADAM10 is implicated.
Abstract: To improve clinic note sharing efficacy, this systematic literature review (a) characterizes the relationship between health literacy and social determinants of health by generating roles for health literacy and (b) identifies feasible health literacy-based interventions to address low patient understanding of health. We examined two databases, Scopus and PubMed, for articles relating to health literacy and social determinants of health. We conducted a quantitative analysis of study characteristics and qualitative analysis using narrative synthesis and theme visualization. A total of 43 eligible studies were analyzed. Four roles for health literacy were identified from these studies: correlate of social determinants of health (n=30), mediator of social determinants of health (n=5), result of social determinants of health (n=5), or modifiable social determinant of health (n=2). Studies also recommended health-literacy based interventions that target policy structure, patient population composition, health education, and health information language. The multivariable nature of health literacy indicates that it could form the basis for many interventions to combat low patient understandability, including interventions using informatics-based solutions: 1) text and language simplification, 2) population-based and cross-cultural communication, 3) patient identification, and 4) health education and online community building. Health literacy is a crucial, multidimensional skill in supporting patient understanding of health materials. Designing interventions aimed at improving health literacy or addressing poor health literacy in patients can help increase comprehension of health information, including the information contained in clinic notes that are shared with patients.
Afternoon Session (1-2 p.m.)
Room 425: Innovation and Access
Leslie Brown, Biological Sciences
Project Advisor: Dr. Daniel Buchholz
Abstract: We developed and optimized a protocol for fluorescently labelling RNA in-situ. This allows for very clear and precise visualization of the molecular mechanisms present in a developing embryo. We can use this information to help elucidate spatial and temporal patterns in RNA expression, which can help build molecular "maps" to understand expression patterns. We used this approach to investigate the pathways active during tracheal-esophageal separation, an early developmental event that often leads to birth defects and spontaneous abortion when it proceeds incorrectly. It is important that we begin to understand these pathways for better clinical and therapeutic interventions, and this approach is a new and effective way of doing so.
Catherine Xu, Medical Sciences
Project Advisor: Dr. Danny Wu
Abstract: Well-being is multi-dimensional and is influenced by many factors that interact together within one's environment. This study aimed to develop a web application to consistently collect clinical well-being levels and provide real-time feedback to clinicians and administrators. A user-centered Well-being Check app was developed with two components: survey and summary visualization. The survey monitored the wellbeing levels of clinicians, and the visualization displayed a summary of survey responses in interactive, cloud-based charts. Once enough data is accumulated, a large-scale analysis will be conducted with connections to the electronic health records to help inform organizational interventions.
Madhulika Singh, Anthropology
Project Advisor: Dr. Shailaja Paik
Abstract: The North-Eastern states of India have been under the Armed Forces (Special Powers) Act (AFSPA) since soon after India's independence meaning that for them, freedom is not yet a reality. This has not been an unquestioned status-quo with constant agitation and organising against the act being the state of affairs almost since its introduction. This project seeks to examine both the ways in which the act has been enacted and challenged through the decades and ultimately aims to see what the future entails with regards to the removal of AFSPA.
Madison Sobieski, Political Science
Project Advisor: Dr. Amy Lind
Abstrac: I intend to discuss why emphasis needs to be placed on the studying of ability within intersectionality as well as give examples of how ability is part of identity.To further the discussion of how disability plays a role in identity and thus intersectionality, I am going to focus on Deafness. There is an immense sense of culture within the Deaf* world, which is why I think it specifically brings an interesting perspective to the table of ability and disability. Thus, making Deafness a larger part of one's identity than other disabilities may be to another person. I want to focus on the intersectionality of Deafness and how Deaf* people feel their Deafness ties into their identity. Lastly, I would like to specifically draw on the experiences of Deaf* women and how the intersection of Deafness and gender affect them in their daily lives. I would like to touch on the historical disparity in treatment of Deaf* women and Deaf* men. Generally, people hold the perception that there is inequality and injustice to people that have disabilities, I would like to focus on this perception and draw attention specifically to the mistreatment and inequalities that Deaf* women face and thus how those things have become essential to their own identities.