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UC project targets pesky mosquitoes’ genes

February 21, 2022

Researchers at the University of Cincinnati examined genetic material of three species of mosquitoes responsible for killing millions of people around the world each year. In a collaboration between UC’s chemistry and biology departments, researchers revealed the surprising genetic modifications female mosquitoes undergo, in part to create the next generation. Using tools called liquid chromatography-tandem mass spectrometry, researchers found as many as 33 genetic modifications in the transfer RNA of female mosquitoes. Like DNA, transfer RNA serves as the building blocks of life, communicating the genetic code from DNA to build new proteins that regulate the body’s tissues and organs.