Biomedical Diagnosis using Noval Nanotubes

Link to faculty eProfessional résumé

Dr. Donglu Shi

Professor COE Chemical & Material Engineering
College of Engineering
dong.shi@uc.edu
+1 (513) 556-3100

A novel design of nanostructure was developed for early detection of cancer and treatment. In this design, key functionalities were constructed at nanoscale, which satisfy the major requirements of biomedical diagnosis including luminescence and drug storage. In vivo imaging in life mice was achieved by intravenously injecting quantum dot (QD) conjugated carbon nanotubes (CNTs) for the first time. With near infrared emission around 800 nm, the CNTs with surface conjugated QD (CNT-QD) exhibited strong luminescence for non-invasive optical in vivo imaging. The surface conjugation was via a novel plasma polymerization approach that deposited ultra thin acrylic acid films (~3 nm) on CNTs.

Project commenced on January 14, 2008

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