Fierce Biotech: Making 'cold' tumors responsive to immunotherapy
UC research points to combination therapy involving the immune system for breast cancer
Some cancers create a hostile environment that allows them to evade immune attacks. That's why many patients with cancer don't respond to immuno-oncology treatments. Scientists are looking for ways to turn these so-called “cold” tumors into “hot” ones that are susceptible to immunotherapy.
A research study by scientists at the University of Cincinnati have discovered proteins that can be targeted to overcome resistance to cancer immunotherapy in animal models.
Syn Kok Yeo, PhD, research instructor in the department of cancer biology at the UC College of Medicine and a member in the lab of Jun-Lin Guan, PhD, the Francis Brunning Professor and Cancer Biology Department Chair, describes his research. He is a member of the UC Cancer Center.
Featured photo of stress fibers and microtubules in human breast cancer cells. Courtesy of the National Cancer Institute.
Next Lives Here
The University of Cincinnati is classified as a Research 1 institution by the Carnegie Commission and is ranked in the National Science Foundation's Top-35 public research universities. UC's graduate students and faculty investigate problems and innovate solutions with real-world impact. Next Lives Here.
Related Stories
UC celebrates National Postdoc Appreciation Week
September 19, 2024
The University of Cincinnati has a long list of events lined up to honor its postdoctoral fellows as colleges across the country celebrate National Postdoc Appreciation Week.
Cognitive decline reduced by MIND diet, study finds
September 19, 2024
National outlets including CNN, Newsweek and U.S. News & World Report highlighted research led by the University of Cincinnati's Russell Sawyer that found following the MIND diet for 10 years produced a small but significant decrease in the risk of developing thinking, concentration and memory problems.
Nationwide map shows area's risks of landslides
September 19, 2024
UC Associate Professor Daniel Sturmer talks to WVXU about a new national map identifying areas at greatest risk for landslides.