Engineers develop stress test to measure cortisol

Device could help diagnose depression, cardiac issues

Yahoo! Finance and other news outlets highlighted devices developed by engineers at the University of Cincinnati to test cortisol and cardiac issues.

UC College of Engineering and Applied Science Distinguished Research Professor Chong Ahn and his students developed a “lab-on-a-chip” device that measures the stress hormone cortisol from a patient’s saliva. Knowing if a patient has elevated stress hormones can provide useful diagnostic information even if patients do not report feelings of anxiety, stress or depression in a standard mental health questionnaire.

Mental health disorders affect more than 400 million people around the world. Stress disorders such as anxiety and depression are among the leading causes of disability worldwide. Prolonged cortisol elevation is linked to numerous mental health disorders, including depression and anxiety.

UC researchers created a lab-on-a-chip system to track a patient’s cortiso levels. It consists of a disposable collection device that a person puts in their mouth which is then inserted into a reader. The reader can transmit results in minutes to a portable analyzer and phone.

The study was published in the journal Biomedical Microdevices.

Featured image at top: UC doctoral student Heeyong Jang holds up a microfluidic device developed in Chong Ahn's lab. Photo/Andrew Higley/UC Marketing + Brand

Read the Yahoo! Finance story.

UC College of Engineering and Applied Science Professor Chong Ahn is developing a new test that can measure stress hormones from saliva.
Also pictured:
Doctoral student Heeyong Jang
Doctoral student Supreeth Setty (beard)
Master's student Varsha Lingam

Distinguished Research Professor Chong Ahn is working on point-of-care tests in his electrical engineering lab. Photo/Andrew Higley/UC Marketing + Brand

More UC Electrical Engineering in the news

UC College of Engineering and Applied Science Professor Chong Ahn is developing a new test that can measure stress hormones from saliva.
Also pictured:
Doctoral student Heeyong Jang
Doctoral student Supreeth Setty (beard)
Master's student Varsha Lingam

UC doctoral students Heeyong Jang, left, and Supreeth Setty work in Chong Ahn's electrical engineering lab. Photo/Andrew Higley/UC Marketing + Brand

Related Stories

1

Materials scientist gains valuable research experience

May 20, 2026

The opportunities at the College of Engineering and Applied Science are what attracted Ananth Balasubramanian to the University of Cincinnati. He came to UC as a master's student and after two years, transitioned to a direct PhD program in materials science and engineering. Here, he works in the Digital Fabrication Laboratory and recently was named Graduate Student Engineer of the Month by CEAS.

2

6 ways starting a GLP-1 medication could affect your emotions

May 20, 2026

When patients first start taking a glucagon-like peptide-1 (GLP-1) medication, they probably expect to feel full. But they might not anticipate how it can influence their emotions. The medications act on the stomach and the brain, said Malti Vij, MD, a University of Cincinnati adjunct associate professor in the College of Medicine's Department of Internal Medicine and a diplomate of the American Board of Obesity Medicine.

3

Engineering alumnus instrumental in NASA Artemis mission

May 19, 2026

Space, rockets, and NASA have been a lifelong fascination for John McCullough '89. He was inspired after watching the moon landing as a child and learning about aerospace engineering. He graduated from the University of Cincinnati with a degree in aerospace engineering and has worked at NASA for more than 36 years. He has played key roles in many missions including Artemis I and the most recent Artemis II.