Engineers develop stress test to measure cortisol

Device could help diagnose depression, cardiac issues

Yahoo! Finance and other news outlets highlighted devices developed by engineers at the University of Cincinnati to test cortisol and cardiac issues.

UC College of Engineering and Applied Science Distinguished Research Professor Chong Ahn and his students developed a “lab-on-a-chip” device that measures the stress hormone cortisol from a patient’s saliva. Knowing if a patient has elevated stress hormones can provide useful diagnostic information even if patients do not report feelings of anxiety, stress or depression in a standard mental health questionnaire.

Mental health disorders affect more than 400 million people around the world. Stress disorders such as anxiety and depression are among the leading causes of disability worldwide. Prolonged cortisol elevation is linked to numerous mental health disorders, including depression and anxiety.

UC researchers created a lab-on-a-chip system to track a patient’s cortiso levels. It consists of a disposable collection device that a person puts in their mouth which is then inserted into a reader. The reader can transmit results in minutes to a portable analyzer and phone.

The study was published in the journal Biomedical Microdevices.

Featured image at top: UC doctoral student Heeyong Jang holds up a microfluidic device developed in Chong Ahn's lab. Photo/Andrew Higley/UC Marketing + Brand

Read the Yahoo! Finance story.

UC College of Engineering and Applied Science Professor Chong Ahn is developing a new test that can measure stress hormones from saliva.
Also pictured:
Doctoral student Heeyong Jang
Doctoral student Supreeth Setty (beard)
Master's student Varsha Lingam

Distinguished Research Professor Chong Ahn is working on point-of-care tests in his electrical engineering lab. Photo/Andrew Higley/UC Marketing + Brand

More UC Electrical Engineering in the news

UC College of Engineering and Applied Science Professor Chong Ahn is developing a new test that can measure stress hormones from saliva.
Also pictured:
Doctoral student Heeyong Jang
Doctoral student Supreeth Setty (beard)
Master's student Varsha Lingam

UC doctoral students Heeyong Jang, left, and Supreeth Setty work in Chong Ahn's electrical engineering lab. Photo/Andrew Higley/UC Marketing + Brand

Related Stories

1

‘Mini-brain’ shines light on concussions

April 8, 2026

University of Cincinnati biomedical engineers developed a “mini-brain” model to study concussions and traumatic brain injury (TBI) from blunt-force trauma, revealing how cellular damage and inflammation may lead to long-term neurodegenerative disease.

2

Engineering students shine at annual CEAS EXPO

April 8, 2026

Every spring, the College of Engineering and Applied Science hosts a large-scale capstone showcase for graduating seniors to show off their final projects as a culmination of their five years at the University of Cincinnati. The 2026 EXPO, presented by DRT Holdings, marks the largest event yet featuring more than 250 student projects, ranging from student-built vehicles to innovative robotic devices, to building renovation plans, and interdisciplinary research.

3

The psychological weight of money

April 7, 2026

Psychology and neuroscience website PsyPost highlighted research led by Sharmeen Merchant, doctoral candidate in UC’s Carl H. Lindner College of Business, that suggests a man’s sense of fulfillment at work is intertwined with his partner’s views on money.