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Neurology Today: Depolarizations and brain injury

UC's Jed Hartings, PhD, featured.

Spreading depolarizations have been a “silent culprit” in brain injury for years, but a growing awareness has put the phenomenon back on the radar screen after it was first noticed more than 70 years ago, an expert said at the American Academy of Neurology annual meeting in May.

Jed Hartings, PhD, associate professor of neurosurgery at the University of Cincinnati College of Medicine, said the first glimpse of the phenomenon dates back to 1944, when Aristides Leao, PhD, first described “spreading depression of activity in the cerebral cortex.”

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