NBC News: New Alzheimer's drug comes with steep price tag

UC expert says doctors, patients will have to consider financial burden when making decision

Leqembi, a newly approved drug for use in people with mild cognitive impairment or early Alzheimer's disease, comes with a price of $26,500 a year.

Experts say the high price, along with Medicare only covering the drug for patients enrolled in a clinical trial, will mean only a limited number of patients will be able to get the drug when it becomes available.

The University of Cincinnati's Alberto Espay, MD, professor of neurology in the UC College of Medicine, director and endowed chair of the James J. and Joan A. Gardner Family Center for Parkinson’s Disease and Movement Disorders at the UC Gardner Neuroscience Institute and a UC Health physician, told NBC News the price of the drug is "very unfortunate."

Espay said doctors will need to include the financial burden as a possible risk of the drug when discussing its potential benefits of modestly slowing the disease. He is a proponent of an alternative theory that it is the loss of the normal amyloid protein, rather than the build-up of the abnormal amyloid plaques, that leads to degeneration.

Previously, Espay noted the benefits of Leqembi may stem from the fact that it increases levels of the normal protein in the brain in addition to its primary aim of removing plaques.

Read the NBC News article on the price of Leqembi.

Read the NBC News article featuring Espay about unanswered questions about Leqembi.

Espay also discussed Leqembi and the state of Alzheimer's research on WVXU's Cincinnati Edition. Listen to the Cincinnati Edition segment.

Read more about Espay's research and alternative Alzheimer's hypothesis.

Featured photo at top courtesy of Unsplash.

Related Stories

1

Tips to avoid headaches this holiday season

December 15, 2025

A University of Cincinnati migraine expert offered a list of potential headache triggers around the holidays, and how you can try to avoid them, to 91.7 WVXU News. "There are a number of different factors that make this a very headache provocative time," said Vincent Martin, MD, professor of clinical medicine at the University of Cincinnati's College of Medicine and director of the Headache and Facial Pain Center at the Gardner Neuroscience Institute.

2

Local couple uses royalties from children's books to give gifts to kids in need

December 15, 2025

A local couple has found a unique way to give back to those in need this holiday season. Vic and Laura Troha wrote two children's books together, and this year, they are using the proceeds to buy Christmas gifts for Hamilton County foster kids. The couple are both graduates of the University of Cincinnati's College of Allied Health Sciences and met the day they graduated.

3

The hottest toys this holiday season

December 15, 2025

Local 12 turned to Lindner College of Business associate professor-educator of marketing Roseann Hassey to explain what’s got the trendiest items flying off the shelves.