NBC News: Effects of psychedelic drugs can last for days or weeks, research finds

An off-duty Alaska Airlines pilot accused of trying to bring down a plane midflight said he had consumed “magic mushrooms” before boarding, bringing the use of psychedelic drugs as a treatment for mental illness into national headlines.

Psychedelics such as LSD, psilocybin found in magic mushrooms and MDMA are gaining increasing attention in scientific and medical circles because of the potential they hold for treating anxiety disorders and emotional trauma. Experts say the effects of psychedelics can last for days, weeks or longer after the substance is no longer detectable in the body.

The University of Cincinnati's Christopher Tuell, assistant professor of psychiatry and behavioral neuroscience in UC's College of Medicine and clinical director of addiction services at UC Health's Lindner Center of HOPE, spoke with NBC News about the use of psychedelics as mental health treatment.

Tuell said the brain develops habits that are key to survival, but sometimes the wiring results in unhealthy connections becoming strengthened, leading to issues including depression or anxiety. It’s like a car wheel stuck in a rut in the road, unable to pull out, Tuell said.

Psychedelics can help get the brain "unstuck" from this cycle of negative thoughts, moods and behaviors when used in the right context, experts say.

Read the NBC News article.

Read more about psychedelics research.

Featured photo at top of mushrooms. Photo/Christopher Ott/Unsplash.

Related Stories

1

What would expanded access to GLP-1s mean for the obesity rate?

December 4, 2025

The World Health Organization recently issued its first guidance on GLP-1 medications for adults with obesity — recommending long-term, continuous use when clinically appropriate. Malti Vij, MD, University of Cincinnati adjunct associate professor in the College of Medicine's Department of Internal Medicine, appeared on Cincinnati Edition on 91.7 WVXU News to discuss GLP-1s and what expanded insurance coverage of the medications might mean for Americans.

2

Teaching empathy and courage

December 4, 2025

Two University of Cincinnati co-op students engage children in hands-on “Superhero Activation” activities at the Nancy & David Wolf Holocaust & Humanity Center, helping young visitors learn kindness, courage and how to be upstanders.