Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

UC expert comments on study to NBC News

The University of Cincinnati's Alberto Espay, MD, commented to NBC News on new research published Oct. 24 that found semaglutide, the active ingredient in Ozempic and Wegovy, appeared to reduce the risk of Alzheimer’s disease in people with Type 2 diabetes.

The new study compared semaglutide to seven other diabetes drugs, including metformin, insulin and older GLP-1 drugs, including liraglutide. 

Researchers found that patients prescribed semaglutide had a significantly lower risk for Alzheimer’s disease than those who had taken one of the seven other diabetes drugs. The results were consistent across gender, age and weight. 

Espay, who was not involved in the study, told NBC News more research is needed to determine if the drugs actually work against Alzheimer's. He noted previous early research showed similar positive effects for people who took drugs including statins or insulin, but none of those potential treatments panned out.

“Just as with statins, NSAIDs and insulin, we should be cautious about claiming semaglutide can treat or prevent Alzheimer’s based on this study alone,” Espay said. 

Read the NBC News story.

Featured photo at top of a semaglutide injection pen. Photo/aprott/iStock.

Related Stories

1

The psychological weight of money

April 7, 2026

Psychology and neuroscience website PsyPost highlighted research led by Sharmeen Merchant, doctoral candidate in UC’s Carl H. Lindner College of Business, that suggests a man’s sense of fulfillment at work is intertwined with his partner’s views on money.

2

'Born to Bowl' docu-series from CCM alum Brian Lazarte airs on HBO

April 7, 2026

The HBO Original five-part documentary series "Born to Bowl," directed by CCM Media Production alumnus Brian Lazarte and James Lee Hernandez, from A24 and executive produced by Ben Stiller, and narrated by Liev Schreiber, airs its final episode on Monday, April 13. It will be available to watch on HBO as well as stream on HBO Max.

3

'My health is priceless'

April 7, 2026

Weight loss drugs, including Ozempic and Wegovy, are changing more than waistlines — they're quietly transforming how people spend money, what they prioritize and who can afford better health. As Local 12/WKRC-TV recently reported, for some patients, the medications are life-changing. For others, the cost can be overwhelming.