Funding helps put UC near the forefront of cancer research
Chemistry professor In-Kwon Kim advances breast cancer research through ACS grant
By Benjamin Harrison
The ongoing fight against cancer isn’t going to go away anytime soon, but work by chemists at the University of Cincinnati could lead to important advances.
In-Kwon Kim, assistant professor of chemistry in UC's College of Arts and Sciences, has received a four-year, nearly $800,000 grant from the American Cancer Society. With the help of this grant, Kim and his team hopes to put UC the head of the next-stage cancer treatment.
Kim’s research group focuses primarily on the ADP-ribosylation cycle that regulates many cellular signaling pathways, including DNA repair and cell death. Kim and his team are working with human enzymes that remove different types of ADP-ribosylations. These enzymes play key roles in DNA repair and are often associated with breast cancer.
In the world of cancer research, it can take time for promising results. But with the help of his team and the Cancer Foundations, Kim has started to see signs that things are moving in the right direction.
“A defective DNA repair is a hallmark of cancer,” Kim said. “So far, drugs targeting the DNA repair defects have shown promise in cancer treatment. However, they also have limitations. Cancer cells frequently develop drug resistance. Our research has been focused on the development of alternatives to current cancer drugs in the market.”
Indeed, Kim and his team published a paper on selective PARG inhibitors last year in the journal Nature Communications.
Kim is leading a research group with six graduate students and also participates in teaching biochemistry courses.
“Both for cancer research and education, the most important question is how we can leverage our information to develop safer and more effective drugs to combat diseases. And this is just what we are doing with our cancer research.” said Kim.
“I believe that our efforts to develop new tumor-selective drugs will provide better therapeutic options to breast cancer patients in the future.”
Featured image at top: Aerial view of UC's uptown campus.
UC students explore career paths through NeuroSociety Club
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By: Joí Dean As a freshman, Victoria Popritkin, the current president of NeuroSociety , a third-year neuroscience and vocal performance major, was in search of an organization that would complement both of her future career choices. Right away Popritkin felt that the student organization NeuroSociety, was a place for people with a variety of different career paths and not a road that would only lead to medical school. According to CampusLink, NeuroSociety, is a group of undergraduate students looking to learn more about the brain and the career fields associated with neuroscience through speakers, movies and hands-on activities.
Future of Nursing 2020-2030 report to be released
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The Future of Nursing 2020-2030: “Charting a Path to Achieve Health Equity” is being released on Tuesday, May 11. Greer Glazer, PhD, dean of the University of Cincinnati College of Nursing is one of the 15 people who served on the committee composing the report. The report explores how nurses can work over the next decade to reduce health disparities and promote equity, while keeping costs at bay, utilizing technology and maintaining patient and family-focused care.
UC faculty, staff can dine for $8 at On the Green
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