MSN, Neurology Live highlight UC Parkinson's trial results
MSN and Neurology Live covered the results of a phase 3 trial co-led by a University of Cincinnati researcher that found Parkinson’s disease medication delivered through an infusion pump is safe and effective at reducing symptoms for longer periods of time.
The trial, led by UC's Alberto Espay, MD, found that 24-hour, continuous levodopa delivered through a subcutaneous infusion pump led to nearly two additional hours per day of "on time," or the time when the medication is working and symptoms are lessened, compared to taking levodopa orally.
“Levodopa is a replacement strategy. We all make levodopa, but Parkinson's patients make less of it,” said Espay, co-principal investigator of the trial, James J. and Joan A. Gardner Family Center for Parkinson’s Disease Research Endowed Chair in UC’s Department of Neurology and Rehabilitation Medicine and a physician at the UC Gardner Neuroscience Institute.
“Once approved, this will become an important treatment strategy to consider for patients with Parkinson’s disease experiencing motor fluctuations not adequately controlled with medication,” Espay continued. “Future studies will need to determine the durability of the long-term benefits and whether any safety issues could emerge, as well as how it might compare with deep brain stimulation.”
Read the MSN story, originally published on News Medical.
Read the Neurology Live story.
Healio, Physicians Weekly, Parkinson's News Today and Cleveland.com also covered the research.
Read the Parkinson's News Today article.
Read the Physicians Weekly article, originally published on Health Day.
Featured photo at top of 3-D illustration of a dopamine molecule. Photo/Dr_Microbe/iStock.
Related Stories
Three years, countless stories
May 15, 2026
UC's Klekamp Law celebrates its 193rd Hooding with stories from graduates reflecting on their paths through the college.
Driven by curiosity, guided by care
May 14, 2026
Max Wilson, a University of Cincinnati College of Allied Health Sciences health sciences major on the pre-physician assistant track, found his path expanding beyond the classroom and into hands-on research focused on human performance and patient care.
UC Blue Ash celebrates top students and recognizes Honor Student of the Year
May 14, 2026
The University of Cincinnati Blue Ash College recently hosted a special event that celebrated students for exceptional achievements during the 2025-26 academic year. The honorees included academic award winners, student engagement award winners, Latin Honors graduates, and the 2026 UC Blue Ash College Honor Student of the Year.