Action News 5: PEP Buddy helps people breathe easier

UC Venture Lab-backed startup aims to help people affected by COPD

A hands-free device developed by researchers at the University of Cincinnati could help the 12.5 million Americans who have chronic obstructive pulmonary disease breathe easier, Action News 5 in Memphis, Tennessee, reported.

PEP Buddy, a UC Venture Lab-backed startup, was created by Muhammad Ahsan Zafar, MD, and Ralph J. Panos, MD.

With COPD, it takes longer for people to get inhaled air out of their lungs. With each breath, extra air is retained in the lungs. This “air stacking” during activities (dynamic hyperinflation) is the primary reason for breathlessness in people with COPD and also leads to decreased oxygen levels.

PEP Buddy gives a gentle back pressure while the user breathes out, which assists in keeping open air tubes in the lungs and preventing them from collapsing. The device also prolongs the exhalation phase and reduces the breathing rate, decreasing the effects of air stacking.

“It’s just simply placed in the mouth, one breath in through the nose, and then out through the device. That resistance to airflow creates the back pressure, which relieves the air trapping and dynamic hyperinflation,” Panos said.

See more from Action News 5.

  Featured image at top: PEP Buddy device. Photo/PEP Buddy

Innovation Lives Here

The University of Cincinnati is leading public urban universities into a new era of innovation and impact. Our faculty, staff and students are saving lives, changing outcomes and bending the future in our city's direction. Next Lives Here.

Related Stories

2

Make Hoxworth Blood Center’s special holiday events part of your family celebrations this December

December 12, 2025

This December, Hoxworth Blood Center, University of Cincinnati, is inviting families across Greater Cincinnati to add something truly meaningful to their holiday traditions: giving the gift of life. With festive community events, beloved local partners and special thank-you gifts for donors, Hoxworth is making it easier, and more heartwarming than ever, to roll up your sleeves and help save lives close to home.

3

Ohio nurses weigh in on proposed federal loan rule

December 12, 2025

Spectrum News journalist Javari Burnett spoke with UC Dean Alicia Ribar and UC nursing students Megan Romero and Nevaeh Haskins about proposed new federal student loan rules. Romero and Haskins, both seniors, were filmed in the College of Nursing’s Simulation Lab.